This mutation is a deletion that includes the D17Aus9 locus. It was generated by homologous recombination of a neomycin/thymidine kinase selection cassette into the D17Aus9 locus in ES cells, then irradiating these cells and selecting for cell lines that no longer expressed thymidine kinase. These ES cell lines were then used to create chimeric mice. See mapping details/ breakpoints in J:36910. (J:36910)

Basic Information

Allele
Strain of Origin
Allele Type
Mutation
Inheritance
Gene Expression
Related Disease
Reference
(BALB/cJ x 129S4/SvJae)F1
Radiation induced
Deletion
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--
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1

Phenotypes

Legend:
hm: homozygous
ht: heterozygous
cn: conditional genotype
cx: complex: > 1 genome feature
tg: involves transgenes
ot: other: hemizygous, indeterminate,...
(F): Female
(M): Male
phenotype observed
N: normal phenotype
(#): related diseases count
Phenotypes:
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Phenotypes

References Literature

Title
PMID
Journal
Year
IF
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