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An asparagine to methionine substitution within the second transmembrane domain was achieved by the introduction of 2 nucleotide substitutions (AAC to ATG) in exon 8 at codon 265 (N265M). A single loxP site remained downstream of exon 8 after a floxed neo cassette was excised via in vivo cre mediated recombination. (J:81497)
Basic Information
Allele
Strain of Origin
Allele Type
Mutation
Inheritance
Related Gene
Related Disease
Reference
Phenotypes
Legend：
hm: homozygous
ht: heterozygous
cn: conditional genotype
cx: complex: > 1 genome feature
tg: involves transgenes
ot: other: hemizygous, indeterminate,...
(F): Female
(M): Male
phenotype observed
N: normal phenotype
(#): related diseases count
Phenotypes：
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| Phenotypes |
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References Literature
Title
PMID
Journal
Year
IF
