This allele is a derivative of Igf1tm1Dlr in which the loxP flanked sequences were deleted in the germline by crossing mice carrying Igf1tm1Dlr to mice carrying the TgN(EIIa-cre)C5379Lmgd transgene. A truncated, non functional protein is produced. (J:49468)

Basic Information

Allele
Strain of Origin
Allele Type
Mutation
Inheritance
Related Gene
Related Disease
Reference
Not Specified
Targeted
Intragenic deletion
--
1
2
5

Phenotypes

Legend:
hm: homozygous
ht: heterozygous
cn: conditional genotype
cx: complex: > 1 genome feature
tg: involves transgenes
ot: other: hemizygous, indeterminate,...
(F): Female
(M): Male
phenotype observed
N: normal phenotype
(#): related diseases count
Phenotypes:
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Phenotypes

References Literature

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PMID
Journal
Year
IF
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