Tg(TIE2-lacZ)182Sato

The transgene consists of a mouse Tek promoter (2.1 kb HindIII segment including most of exon1), a lacZ reporter gene, a Tek1 enhancer element, and an SV40 polyadenylation sequence. The enhancer element is 1.7 kb genomic sequence (XhoI-KpnI restriction fragment) from inside the 5' half of intron 1. Expression was driven in endothelial cells. (J:39276)