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A mouse Col2a1 gene deleted for a 150 bp region containing exon 7 and intron 7 was used for the transgene. 3 kb of mouse Col2a1 promoter sequences were used to drive transgene expression in chondrocytes. The transgene is expressed predominantly in the cartilage and eye as determined by RT-PCR analysis of transgenic tissues. (J:1279)
Basic Information
Allele
Strain of Origin
Allele Type
Mutation
Inheritance
Gene Expression
Related Disease
Reference
Phenotypes
Legend：
hm: homozygous
ht: heterozygous
cn: conditional genotype
cx: complex: > 1 genome feature
tg: involves transgenes
ot: other: hemizygous, indeterminate,...
(F): Female
(M): Male
phenotype observed
N: normal phenotype
(#): related diseases count
Phenotypes：
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| Phenotypes |
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References Literature
Title
PMID
Journal
Year
IF
