The floxed PGK-neo cassette was deleted by mating Gt(ROSA)26Sortm1(EYFP)Cos animals to the Tg(ACTB-cre)2Mrt line. Removal of the tpA stop sequence within the floxed neo cassette allows transcription of the EYFP reporter gene. (J:80963, J:98830)
Legend:
cx: complex: > 1 genome feature ot: other: hemizygous, indeterminate,... (F): Female
(M): Male
N: normal phenotype
(#): related diseases count