Exon 18 was disrupted by a neomycin selection cassette inserted by homologous recombination. Neither normal transcript nor normal protein was detected by Northern and Western blot analyses of liver tissue obtained from homozygous mutant mice. (J:81174)
Basic Information
(C57BL/6NCrlj x CBA/JNCrlj)F1
Legend:
cx: complex: > 1 genome feature ot: other: hemizygous, indeterminate,... (F): Female
(M): Male
N: normal phenotype
(#): related diseases count