The transgene consists of a human MYC genomic sequence and a 5.5 kb fragment containing the human CD2 dominant control region to drive expression in T lymphocytes. Northern blot analysis using a human MYC exon 1 probe revealed transgene expression in all thymic tumors, but not in healthy tissues. (J:81276)

Basic Information

Allele
Strain of Origin
Allele Type
Mutation
Inheritance
Gene Expression
Related Disease
Reference
(C57BL/6J x CBA/Ca)F2
--
Insertion
--
1
--
6

Phenotypes

Legend:
hm: homozygous
ht: heterozygous
cn: conditional genotype
cx: complex: > 1 genome feature
tg: involves transgenes
ot: other: hemizygous, indeterminate,...
(F): Female
(M): Male
phenotype observed
N: normal phenotype
(#): related diseases count
Phenotypes:
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Phenotypes

References Literature

Title
PMID
Journal
Year
IF
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