The transgene consists of a human MYC genomic sequence and a 5.5 kb fragment containing the human CD2 dominant control region to drive expression in T lymphocytes. Northern blot analysis using a human MYC exon 1 probe revealed transgene expression in all thymic tumors, but not in healthy tissues. (J:81276)
Legend:
cx: complex: > 1 genome feature ot: other: hemizygous, indeterminate,... (F): Female
(M): Male
N: normal phenotype
(#): related diseases count