The transgene consists of a mouse Edn1 promoter, active in the vascular wall, and a bovine NOS3 cDNA. RNase protection assay detected transgene expression in heart, lung, aorta, and uterus. Low levels of transgene expression was also observed in brain, liver, kidney, and intestine. (J:81132)

Basic Information

Allele
Strain of Origin
Allele Type
Mutation
Inheritance
Gene Expression
Related Disease
Reference
(C57BL/6 x DBA/2)F1
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Insertion
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23

Phenotypes

Legend:
hm: homozygous
ht: heterozygous
cn: conditional genotype
cx: complex: > 1 genome feature
tg: involves transgenes
ot: other: hemizygous, indeterminate,...
(F): Female
(M): Male
phenotype observed
N: normal phenotype
(#): related diseases count
Phenotypes:
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Phenotypes

References Literature

Title
PMID
Journal
Year
IF
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