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The transgene contains a 79.5 kb P1 insert with the entire human APOB gene. RNA slot blot analysis detected transgene expression in the liver, with very small amounts expressed in the small intestine and heart. Western blot analysis of plasma from transgenic animals showed human apo-B100 as the predominant species of transgene product. (J:81265)
Basic Information
Allele
Strain of Origin
Allele Type
Mutation
Inheritance
Gene Expression
Related Disease
Reference
Phenotypes
Legend：
hm: homozygous
ht: heterozygous
cn: conditional genotype
cx: complex: > 1 genome feature
tg: involves transgenes
ot: other: hemizygous, indeterminate,...
(F): Female
(M): Male
phenotype observed
N: normal phenotype
(#): related diseases count
Phenotypes：
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| Phenotypes |
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References Literature
Title
PMID
Journal
Year
IF
