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The transgene consists of a rat Pbsn minimal promoter and a dominant negative human FGFR2 (isoform iiib) cDNA. The rat probasin minimal promoter (-426 to +28) was used to drive transgene expression in prostate epithelium. Three lines were established: 3260, 3425, 5806, however, the pound symbol (#) is used when lines are pooled. (J:80821)
Basic Information
Allele
Strain of Origin
Allele Type
Mutation
Inheritance
Gene Expression
Related Disease
Reference
Phenotypes
Legend：
hm: homozygous
ht: heterozygous
cn: conditional genotype
cx: complex: > 1 genome feature
tg: involves transgenes
ot: other: hemizygous, indeterminate,...
(F): Female
(M): Male
phenotype observed
N: normal phenotype
(#): related diseases count
Phenotypes：
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| Phenotypes |
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References Literature
Title
PMID
Journal
Year
IF
