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The transgene consists of an MMTV promoter, a human ERBB3 cDNA, and the bovine growth hormone exon 5 and polyadenylation sequence. The MMTV promoter was used to overexpress the human transgene in lung and mammary glands of transgenic mice. Transgenic animals express human ERBB3 mRNA in lung, mammary gland, brain, intestine, thymus, liver, and spleen as determined by RT-PCR analyisis. (J:80974)
Basic Information
Allele
Strain of Origin
Allele Type
Mutation
Inheritance
Gene Expression
Related Disease
Reference
Phenotypes
Legend：
hm: homozygous
ht: heterozygous
cn: conditional genotype
cx: complex: > 1 genome feature
tg: involves transgenes
ot: other: hemizygous, indeterminate,...
(F): Female
(M): Male
phenotype observed
N: normal phenotype
(#): related diseases count
Phenotypes：
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References Literature
Title
PMID
Journal
Year
IF
