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The transgene consists of a TTR promoter and 2.6 kb of human FOXM1 sequence fused to TTR exon 2. The TTR regulatory region consists 3 kb of the TTR promoter, exon 1, and exon 2. This promoter construct targets transgene expression to hepatocytes. (J:58603)
Basic Information
Allele
Strain of Origin
Allele Type
Mutation
Inheritance
Gene Expression
Related Disease
Reference
Phenotypes
Legend：
hm: homozygous
ht: heterozygous
cn: conditional genotype
cx: complex: > 1 genome feature
tg: involves transgenes
ot: other: hemizygous, indeterminate,...
(F): Female
(M): Male
phenotype observed
N: normal phenotype
(#): related diseases count
Phenotypes：
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References Literature
Title
PMID
Journal
Year
IF
