Exon 1 was disrupted by an enhanced green fluorescent protein (eGFP) gene inserted at the endogenous start codon. A single loxP site remained downstream of eGFP after the removal of a floxed neo cassette. Western blot analysis of lymph node lysates indicated an absence of normal protein in homozygous mutant mice. (J:75364)
Legend:
cx: complex: > 1 genome feature ot: other: hemizygous, indeterminate,... (F): Female
(M): Male
N: normal phenotype
(#): related diseases count