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A full-length cDNA encoding mouse utrophin with an N-terminal FLAG epitope tag was inserted between the cytomegalovirus (CMV) minimal promoter and polyadenylation signal, all downstream of the tetracycline operator (tetracycline responsive element). Tissue-specific tetracycline transactivator (tTA) or reverse transactivator (rtTA) expression from a second transgene permits regulation of utrophin expression by administration of doxycycline in drinking water. (J:80809)
Basic Information
Allele
Strain of Origin
Allele Type
Mutation
Inheritance
Gene Expression
Related Disease
Reference
Phenotypes
Legend：
hm: homozygous
ht: heterozygous
cn: conditional genotype
cx: complex: > 1 genome feature
tg: involves transgenes
ot: other: hemizygous, indeterminate,...
(F): Female
(M): Male
phenotype observed
N: normal phenotype
(#): related diseases count
Phenotypes：
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References Literature
Title
PMID
Journal
Year
IF
