Tg(H2-K-Stat5b)1Wjl

The transgenic construct contained sequence encoding Stat5b driven by a H2-K promoter and followed by an IgH enhancer. Stat5b overexpression was verified in the thymus and spleen by Western blot analysis. Western blot analysis using a an anti-phospho-Stat5b antibody showed that the transgenic protein was phosphorylated upon Il2 stimulation. (J:80897)