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The transgenic construct contained sequence encoding Stat5b driven by a H2-K promoter and followed by an IgH enhancer. Stat5b overexpression was verified in the thymus and spleen by Western blot analysis. Western blot analysis using a an anti-phospho-Stat5b antibody showed that the transgenic protein was phosphorylated upon Il2 stimulation. (J:80897)
Basic Information
Allele
Strain of Origin
Allele Type
Mutation
Inheritance
Gene Expression
Related Disease
Reference
Phenotypes
Legend：
hm: homozygous
ht: heterozygous
cn: conditional genotype
cx: complex: > 1 genome feature
tg: involves transgenes
ot: other: hemizygous, indeterminate,...
(F): Female
(M): Male
phenotype observed
N: normal phenotype
(#): related diseases count
Phenotypes：
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| Phenotypes |
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References Literature
Title
PMID
Journal
Year
IF
