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The transgene consists of the CAG regulatory unit (a CMV early immediate enhancer, and a modified chicken actin beta promoter) as well as human CD81 cDNA flanked by rabbit beta-globin exon 3 sequences. Transgene RNA expression in all organs was verified by Northern blot analysis. Transgene protein expression on the cell surface of thymocytes, peripheral blood lymphocytes, and splenocytes was observed by cytofluorometric analysis. (J:80797)
Basic Information
Allele
Strain of Origin
Allele Type
Mutation
Inheritance
Gene Expression
Related Disease
Reference
Phenotypes
Legend：
hm: homozygous
ht: heterozygous
cn: conditional genotype
cx: complex: > 1 genome feature
tg: involves transgenes
ot: other: hemizygous, indeterminate,...
(F): Female
(M): Male
phenotype observed
N: normal phenotype
(#): related diseases count
Phenotypes：
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References Literature
Title
PMID
Journal
Year
IF
