A Gfap promoter and mouse Ifna1 cDNA sequence cloned between an upstream SV40 intron and downstream SV40 polyadenylation signal was used for the transgene. The GFAP promoter directs transgene expression in the astrocytes. Transgene expression in the brain was confirmed by RNase protection assay. (J:68811)

Basic Information

Allele
Strain of Origin
Allele Type
Mutation
Inheritance
Gene Expression
Related Disease
Reference
(C57BL/6J x BALB/c)F1
--
Insertion
--
1
--
13

Phenotypes

Legend:
hm: homozygous
ht: heterozygous
cn: conditional genotype
cx: complex: > 1 genome feature
tg: involves transgenes
ot: other: hemizygous, indeterminate,...
(F): Female
(M): Male
phenotype observed
N: normal phenotype
(#): related diseases count
Phenotypes:
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Phenotypes

References Literature

Title
PMID
Journal
Year
IF
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