The transgene consists of a liver specific enhancer element and a genomic DNA fragment containing human APOC1 with 3 kb of 5' flanking sequences and 2.5 kb of 3' flanking sequences. RNase protection assay confirmed transgene expression exclusively in the liver. (J:80950)
Legend:
cx: complex: > 1 genome feature ot: other: hemizygous, indeterminate,... (F): Female
(M): Male
N: normal phenotype
(#): related diseases count