The entire Mpz gene (including 6 kb of promoter sequences, all exons and introns, and the natural polyadenylation signal) was used as the transgene. Transgenic line 80.4 carries 14 copies of the integrated transgene. Transgene expression is approximately 0.8-fold that of the endogenous protein. (J:78758)
Legend:
cx: complex: > 1 genome feature ot: other: hemizygous, indeterminate,... (F): Female
(M): Male
N: normal phenotype
(#): related diseases count