The entire Mpz gene (including 6 kb of promoter sequences, all exons and introns, and the natural polyadenylation signal) was used as the transgene. Transgenic line 80.4 carries 14 copies of the integrated transgene. Transgene expression is approximately 0.8-fold that of the endogenous protein. (J:78758)

Basic Information

Allele
Strain of Origin
Allele Type
Mutation
Inheritance
Gene Expression
Related Disease
Reference
FVB/N
--
Insertion
--
1
--
6

Phenotypes

Legend:
hm: homozygous
ht: heterozygous
cn: conditional genotype
cx: complex: > 1 genome feature
tg: involves transgenes
ot: other: hemizygous, indeterminate,...
(F): Female
(M): Male
phenotype observed
N: normal phenotype
(#): related diseases count
Phenotypes:
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Phenotypes

References Literature

Title
PMID
Journal
Year
IF
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