The entire Mpz gene (including 6 kb of promoter sequences, all exons and introns, and the natural polyadenylation signal) was used as the transgene. Transgenic line 80.3 carries 2 copies of the integrated transgene. Transgene expression is approximately 0.3-fold that of the endogenous protein. (J:78758)
Legend:
cx: complex: > 1 genome feature ot: other: hemizygous, indeterminate,... (F): Female
(M): Male
N: normal phenotype
(#): related diseases count