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Coding regions of both Dlx5 and Dlx6 were deleted and replaced with lacZ-floxed-RSV-neo construct via a single homologous recombination event. The gene targeting event also generated a transcriptionally silent genomic duplication spanning both Dlx5 and Dxl6. Absence of gene expression was confirmed by RT-PCR and whole mount in situ hybridization. (J:77244)
Basic Information
Allele
Strain of Origin
Allele Type
Mutation
Inheritance
Related Gene
Related Disease
Reference
Phenotypes
Legend：
hm: homozygous
ht: heterozygous
cn: conditional genotype
cx: complex: > 1 genome feature
tg: involves transgenes
ot: other: hemizygous, indeterminate,...
(F): Female
(M): Male
phenotype observed
N: normal phenotype
(#): related diseases count
Phenotypes：
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| Phenotypes |
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References Literature
Title
PMID
Journal
Year
IF
