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The transgene consists of 0.75 kb of Lck proximal promoter sequences and 0.8 kb of human BCL2L1 cDNA. Introns, exons, and polyadenylation sequences from the human growth hormone gene consitutes the 3' untranslated region of the construct. The Lck promoter was used to drive transgene expression in lymphoid tissues. Transgene expression in the thymus and spleen was verified by Western blot analysis and flow cytometry. (J:78583)
Basic Information
Allele
Strain of Origin
Allele Type
Mutation
Inheritance
Gene Expression
Related Disease
Reference
Phenotypes
Legend：
hm: homozygous
ht: heterozygous
cn: conditional genotype
cx: complex: > 1 genome feature
tg: involves transgenes
ot: other: hemizygous, indeterminate,...
(F): Female
(M): Male
phenotype observed
N: normal phenotype
(#): related diseases count
Phenotypes：
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References Literature
Title
PMID
Journal
Year
IF
