The transgene consists of a duplicated Igh enhancer (Emu), the Pim1 gene, and a mouse Moloney leukemia virus LTR. Transgene expression was confirmed by Northern and Western blot analysis. High expression of Pim1 mRNA was observed in the thymus, bone marrow, and spleen, but not in testis. Pim1 protein expression is observed in both B and T lymphocytes. (J:79624)

Basic Information

Allele
Strain of Origin
Allele Type
Mutation
Inheritance
Gene Expression
Related Disease
Reference
(CBA x C57BL/6LiA)F2
--
Insertion
--
1
--
17

Phenotypes

Legend:
hm: homozygous
ht: heterozygous
cn: conditional genotype
cx: complex: > 1 genome feature
tg: involves transgenes
ot: other: hemizygous, indeterminate,...
(F): Female
(M): Male
phenotype observed
N: normal phenotype
(#): related diseases count
Phenotypes:
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Phenotypes

References Literature

Title
PMID
Journal
Year
IF
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