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The transgene contains the mouse mammary tumor virus promoter and the mouse myelocytomatosis oncogene and the endogenous Myc promoters. The MMTV promoter droved transgenic expression in the spleen, testis, lung, brain, salivary gland, and mammary (J:72130) and preputial gland. Expression of the transgene was not detected in thymus, pancreas, kidney, liver, heart, or muscle. Five to ten copies of the transgene were inserted at the site of integration. The founder mouse that gave rise to this strain carried two insertions of the transgene, which were separated by breeding into lines carrying either Tg(MMTV-cmyc)147-9aLed or Tg(MMTV-cmyc)147-9bLed. (J:29013)
Basic Information
Allele
Strain of Origin
Allele Type
Mutation
Inheritance
Gene Expression
Related Disease
Reference
Phenotypes
Legend：
hm: homozygous
ht: heterozygous
cn: conditional genotype
cx: complex: > 1 genome feature
tg: involves transgenes
ot: other: hemizygous, indeterminate,...
(F): Female
(M): Male
phenotype observed
N: normal phenotype
(#): related diseases count
Phenotypes：
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References Literature
Title
PMID
Journal
Year
IF
