A 14 kb genomic DNA fragment containing the entire human B2M sequence was used for the transgene. Transgene expression was confirmed by Northern blot analysis. The human transgene is over-expressed 2-fold with an expression pattern similar to that of the endogenous gene. (J:80781)
Basic Information
either: (C57BL/6 and DBA/2) or (C57BL/6 and SJL)
Legend:
cx: complex: > 1 genome feature ot: other: hemizygous, indeterminate,... (F): Female
(M): Male
N: normal phenotype
(#): related diseases count