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The coding region of exon 1 was replaced with a cassette containing sequence encoding enhanced GFP (EGFP) followed by neo. Normal protein was undetected by Western blot analysis of brain and platelet samples obtained from homozygous mutant mice. EGFP transcript was present in brain tissue and fluorescence was detected in platelets and megakaryocytes. (J:77282)
Basic Information
Allele
Strain of Origin
Allele Type
Mutation
Inheritance
Related Gene
Related Disease
Reference
Phenotypes
Legend：
hm: homozygous
ht: heterozygous
cn: conditional genotype
cx: complex: > 1 genome feature
tg: involves transgenes
ot: other: hemizygous, indeterminate,...
(F): Female
(M): Male
phenotype observed
N: normal phenotype
(#): related diseases count
Phenotypes：
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| Phenotypes |
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References Literature
Title
PMID
Journal
Year
IF
