Single loxP sites flank exons 5 through 7. The floxed region encodes the large sialyl motif essential for nucleotide sugar binding and the enzymatic activity of the endogenous protein. (J:80884)
Basic Information
(129X1/SvJ x 129S1/Sv)F1-Kitl+
Legend:
cx: complex: > 1 genome feature ot: other: hemizygous, indeterminate,... (F): Female
(M): Male
N: normal phenotype
(#): related diseases count