Log In|Sign Up
EN
A floxed neo cassette was removed from Ebf2tm1Ggc via in vivo cre mediated recombination. The lacZ gene remained in frame and in place of the 5.2 kb fragment containing the coding regions of the first five exons. The deleted region included sequence encoding the majority of the DNA binding domain. The absence of full length transcript was confirmed by RT-PCR analysis of homozygous mutant mice. lacZ expression was determined to be driven by the endogenous promoter. (J:80220)
Basic Information
Allele
Strain of Origin
Allele Type
Mutation
Inheritance
Related Gene
Related Disease
Reference
Phenotypes
Legend：
hm: homozygous
ht: heterozygous
cn: conditional genotype
cx: complex: > 1 genome feature
tg: involves transgenes
ot: other: hemizygous, indeterminate,...
(F): Female
(M): Male
phenotype observed
N: normal phenotype
(#): related diseases count
Phenotypes：
Show/Hide columns
| Phenotypes |
|---|
References Literature
Title
PMID
Journal
Year
IF
