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A 5.3 kb region, containing exon 3 of the Ltb locus and exons 3 and 4 of the Tnf locus, was left floxed after the integration of a targeting vector containing a loxP-neo cassette in intron 2 of the Ltb locus and two downstream loxP sites the intergenic region between Ltb and Tnf and in intron 2 of the Tnf locus. An additional loxP site located within the Lta locus in the targeting vector was not integrated due to partial homologous recombination. (J:58981)
Basic Information
Allele
Strain of Origin
Allele Type
Mutation
Inheritance
Related Gene
Related Disease
Reference
Phenotypes
Legend：
hm: homozygous
ht: heterozygous
cn: conditional genotype
cx: complex: > 1 genome feature
tg: involves transgenes
ot: other: hemizygous, indeterminate,...
(F): Female
(M): Male
phenotype observed
N: normal phenotype
(#): related diseases count
Phenotypes：
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| Phenotypes |
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References Literature
Title
PMID
Journal
Year
IF
