The transgene consists of a rat Ucp1 cDNA sequence under the control of a mouse Ckmm promoter, which drove expression in skeletal muscle and heart. An SV40 polyadenylation signal was added to the Ucp1 construct. Transgene expression in heart and muscle tissues was confirmed by Northern blot analysis. (J:80053)

Basic Information

Allele
Strain of Origin
Allele Type
Mutation
Inheritance
Gene Expression
Related Disease
Reference
(C57BL/6J x DBA/2J)F1
--
Insertion
--
1
--
4

Phenotypes

Legend:
hm: homozygous
ht: heterozygous
cn: conditional genotype
cx: complex: > 1 genome feature
tg: involves transgenes
ot: other: hemizygous, indeterminate,...
(F): Female
(M): Male
phenotype observed
N: normal phenotype
(#): related diseases count
Phenotypes:
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Phenotypes

References Literature

Title
PMID
Journal
Year
IF
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