Hoxd11, Hoxd12, Hoxd13, and regions VIII through XI were deleted via trans-allelic meiotic recombination (TAMERE). The deletion was accomplished by recombination of a single loxP site in the intergenic region between Evx2 and Hoxd13 (Evx2/Hoxd13tm1.1Ddu) and a single loxP on the opposite chromosome downstream of region XI (Hoxdtm5Ddu). (J:80084)
Basic Information
Intergenic deletion, Intragenic deletion
Legend:
cx: complex: > 1 genome feature ot: other: hemizygous, indeterminate,... (F): Female
(M): Male
N: normal phenotype
(#): related diseases count