A single loxP site was left in place of region 12 between Evx2 and Hoxd13 after the floxed neo cassette was excised from Evx2/Hoxd13tm3Ddu via in vivo cre mediated recombination. Expression analysis of Hoxd genes indicated that deletion of region 12 was insufficient to affect Hoxd expression unless coupled with a deletion of regions 11 and 10. (J:80084)

Basic Information

Allele
Strain of Origin
Allele Type
Mutation
Inheritance
Gene Expression
Related Disease
Reference
129S2/SvPas
Targeted
Intergenic deletion
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--
--
2

Phenotypes

Legend:
hm: homozygous
ht: heterozygous
cn: conditional genotype
cx: complex: > 1 genome feature
tg: involves transgenes
ot: other: hemizygous, indeterminate,...
(F): Female
(M): Male
phenotype observed
N: normal phenotype
(#): related diseases count
Phenotypes:
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Phenotypes

References Literature

Title
PMID
Journal
Year
IF
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