Log In|Sign Up
EN
The transgene consists of a human UBC promoter (including exon 1 and intron 1), a 579 bp human CGB cDNA fragment, and a bovine growth hormone polyadenylation signal. Transgene expression was confirmed by RT-PCR and immunohistochemical analysis in several tissues, including the ovary, pituitary gland, liver, kidney, uterus, and testis. Serum of transgenic female animals showeda 40-fold increase in enzyme activity compare to wild-type females. (J:79060)
Basic Information
Allele
Strain of Origin
Allele Type
Mutation
Inheritance
Gene Expression
Related Disease
Reference
Phenotypes
Legend：
hm: homozygous
ht: heterozygous
cn: conditional genotype
cx: complex: > 1 genome feature
tg: involves transgenes
ot: other: hemizygous, indeterminate,...
(F): Female
(M): Male
phenotype observed
N: normal phenotype
(#): related diseases count
Phenotypes：
Show/Hide columns
| Phenotypes |
|---|
References Literature
Title
PMID
Journal
Year
IF
