The transgene consists of a lymphotrophic papovavirus (LPV) enhancer/early promoter and an SV40 T antigen sequence which cannot express the small t antigen due to a deletion of the splice donor site. Regulatory sequences direct expression of the transgene in B- and T-lymphocytes and choroid plexus epithelium. (J:80498)
Legend:
cx: complex: > 1 genome feature ot: other: hemizygous, indeterminate,... (F): Female
(M): Male
N: normal phenotype
(#): related diseases count