Log In|Sign Up
EN
A portion of exon 1 and all of exon 2 was replaced by a hygromycin selection cassette inserted by homologous recombination. The insertion deleted sequence encoding the initiator methionine and the trans-activation domain and introduced a frameshift mutation into all reading frames. Transcript was undetected by both RNAse protection and RT-PCR analysis. (J:67993)
Basic Information
Allele
Strain of Origin
Allele Type
Mutation
Inheritance
Related Gene
Related Disease
Reference
Phenotypes
Legend：
hm: homozygous
ht: heterozygous
cn: conditional genotype
cx: complex: > 1 genome feature
tg: involves transgenes
ot: other: hemizygous, indeterminate,...
(F): Female
(M): Male
phenotype observed
N: normal phenotype
(#): related diseases count
Phenotypes：
Show/Hide columns
| Phenotypes |
|---|
References Literature
Title
PMID
Journal
Year
IF
