The transgene consists of the human CNTN2 proximal promoter and a full-length CNTN1 cDNA sequence. The CNTN2 portion includes exons 1-2. The promoter sequences were used to drive transgene expression the brain. Immunohistochemical analysis of postnatal day 4 animals showed transgene expression throughout most of the external granular layer (EGL). Expression of the transgene was confirmed by RT-PCR. (J:80098)

Basic Information

Allele
Strain of Origin
Allele Type
Mutation
Inheritance
Gene Expression
Related Disease
Reference
(CBA x C57BL/10)F1
--
Insertion
--
1
--
3

Phenotypes

Legend:
hm: homozygous
ht: heterozygous
cn: conditional genotype
cx: complex: > 1 genome feature
tg: involves transgenes
ot: other: hemizygous, indeterminate,...
(F): Female
(M): Male
phenotype observed
N: normal phenotype
(#): related diseases count
Phenotypes:
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Phenotypes

References Literature

Title
PMID
Journal
Year
IF
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