Tg(CNTN2-CNTN1)1Gnn

The transgene consists of the human CNTN2 proximal promoter and a full-length CNTN1 cDNA sequence. The CNTN2 portion includes exons 1-2. The promoter sequences were used to drive transgene expression the brain. Immunohistochemical analysis of postnatal day 4 animals showed transgene expression throughout most of the external granular layer (EGL). Expression of the transgene was confirmed by RT-PCR. (J:80098)