The transgene consists of the human CNTN2 proximal promoter and a full-length CNTN1 cDNA sequence. The CNTN2 portion includes exons 1-2. The promoter sequences were used to drive transgene expression the brain. Immunohistochemical analysis of postnatal day 4 animals showed transgene expression throughout most of the external granular layer (EGL). Expression of the transgene was confirmed by RT-PCR. (J:80098)
Legend:
cx: complex: > 1 genome feature ot: other: hemizygous, indeterminate,... (F): Female
(M): Male
N: normal phenotype
(#): related diseases count