Exon 2 was disrupted by the insertion of a neomycin selection cassette. Neither protein nor phospholipid hydrolytic activity was detected in homozygous mutant mice by Western blot analysis or biochemical assay of pancreatic extracts. (J:68430)
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Exon 2 was disrupted by the insertion of a neomycin selection cassette. Neither protein nor phospholipid hydrolytic activity was detected in homozygous mutant mice by Western blot analysis or biochemical assay of pancreatic extracts. (J:68430)