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The floxed hygromycin gene that replaced the first coding exon was excised from Cer1tm1Rph via in vivo cre mediated recombination. The inserted lacZ gene remained in place of sequence encoding the initiator methionine, signal sequence, prosequence, and the first cysteine of the cystine knot. The expression pattern of lacZ was similar to that of the endogenous gene. (J:62081)
Basic Information
Allele
Strain of Origin
Allele Type
Mutation
Inheritance
Related Gene
Related Disease
Reference
Phenotypes
Legend：
hm: homozygous
ht: heterozygous
cn: conditional genotype
cx: complex: > 1 genome feature
tg: involves transgenes
ot: other: hemizygous, indeterminate,...
(F): Female
(M): Male
phenotype observed
N: normal phenotype
(#): related diseases count
Phenotypes：
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| Phenotypes |
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References Literature
Title
PMID
Journal
Year
IF
