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The transgene was constructed by insertion of an SRC cDNA sequence from the Schmidt-Ruppin strain into exon 1 of GFAP. The GFAP promoter drives expression of the transgene in astrocytes of the brain. RT-PCR analysis of brain RNA from transgenic animals confirmed expression of the transgene. Transgene expression was also detected in lung, thymus, spleen, and gonads. (J:40335)
Basic Information
Allele
Strain of Origin
Allele Type
Mutation
Inheritance
Gene Expression
Related Disease
Reference
Phenotypes
Legend：
hm: homozygous
ht: heterozygous
cn: conditional genotype
cx: complex: > 1 genome feature
tg: involves transgenes
ot: other: hemizygous, indeterminate,...
(F): Female
(M): Male
phenotype observed
N: normal phenotype
(#): related diseases count
Phenotypes：
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References Literature
Title
PMID
Journal
Year
IF
