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This mutant is derived from Rb1tm1Jyjw. The floxed neo cassette in intron 25 was removed by mating Rb1tm1Jyjw animals to cre-expressing line TgN(Prm-cre)58Og. Resulting progeny contain the aspartic acid to alanine mutation in the caspase cleavage site of exon 25 and the diagnostic EcoRI site in intron 24. (J:80087)
Basic Information
Allele
Strain of Origin
Allele Type
Mutation
Inheritance
Related Gene
Related Disease
Reference
Phenotypes
Legend：
hm: homozygous
ht: heterozygous
cn: conditional genotype
cx: complex: > 1 genome feature
tg: involves transgenes
ot: other: hemizygous, indeterminate,...
(F): Female
(M): Male
phenotype observed
N: normal phenotype
(#): related diseases count
Phenotypes：
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References Literature
Title
PMID
Journal
Year
IF
