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Exon 5, which encodes a portion of the homeodomain, was disrupted by the insertion of a cassette containing IRES, cre recombinase, lacZ, and neo. In situ hybridization results showed that the expression pattern of cre was similar to that of the endogenous gene. The neo was removed by crossing to Flp-expressing mice. (J:79853, J:87220)
Basic Information
Allele
Strain of Origin
Allele Type
Mutation
Inheritance
Related Gene
Related Disease
Reference
Phenotypes
Legend：
hm: homozygous
ht: heterozygous
cn: conditional genotype
cx: complex: > 1 genome feature
tg: involves transgenes
ot: other: hemizygous, indeterminate,...
(F): Female
(M): Male
phenotype observed
N: normal phenotype
(#): related diseases count
Phenotypes：
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| Phenotypes |
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References Literature
Title
PMID
Journal
Year
IF
