An allele encoding isoforms a and b, but not the heart- and lung-specific c isoform, was generated by in vivo cre mediated excision of a floxed neo cassette from Pitx2tm3Jfm. The resultant allele contained a single loxP site in place of the c isoform-specific exon 4. (J:79853)

Basic Information

Allele
Strain of Origin
Allele Type
Mutation
Inheritance
Related Gene
Related Disease
Reference
129S4/SvJaeSor
Targeted
Insertion, Intragenic deletion
--
1
9
11

Phenotypes

Legend:
hm: homozygous
ht: heterozygous
cn: conditional genotype
cx: complex: > 1 genome feature
tg: involves transgenes
ot: other: hemizygous, indeterminate,...
(F): Female
(M): Male
phenotype observed
N: normal phenotype
(#): related diseases count
Phenotypes:
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Phenotypes

References Literature

Title
PMID
Journal
Year
IF
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