A promoter-less IRES-lacZ-neo cassette was inserted into exon 8 via homologous recombination. Southern blot analysis was used to identify and confirm the correct gene targeting event in embryonic stem cells. (J:80111)
Legend:
cx: complex: > 1 genome feature ot: other: hemizygous, indeterminate,... (F): Female
(M): Male
N: normal phenotype
(#): related diseases count