Exons 1 through 3 were replaced with a neomycin selection cassette. RT-PCR and in situ hybridization indicated an absence of normal transcript. Protein was undetected in brain tissue obtained from homozygous mutant mice. (J:51659)
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Exons 1 through 3 were replaced with a neomycin selection cassette. RT-PCR and in situ hybridization indicated an absence of normal transcript. Protein was undetected in brain tissue obtained from homozygous mutant mice. (J:51659)