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The endogenous allele was disrupted by the insertion of a PGK-neo cassette into sequences encoding kinase domain 5. RNAse protection showed a 214 bp 5' fragment as well as a 3' fragment expressed from the PGK promoter. Stop codons in the neo cassette preclude the translation of 3' kinase domains. (J:19086)
Basic Information
Allele
Strain of Origin
Allele Type
Mutation
Inheritance
Related Gene
Related Disease
Reference
Phenotypes
Legend：
hm: homozygous
ht: heterozygous
cn: conditional genotype
cx: complex: > 1 genome feature
tg: involves transgenes
ot: other: hemizygous, indeterminate,...
(F): Female
(M): Male
phenotype observed
N: normal phenotype
(#): related diseases count
Phenotypes：
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| Phenotypes |
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References Literature
Title
PMID
Journal
Year
IF
