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Modified rat matrix metalloproteinase 3 (Mmp3) sequence was adjoined to a 2.4 kb murine Wap promoter fragment. The Mmp3 sequence contained a valine to glycine substitution mutation at codon 92 (see Erratum for J:18003), thereby conferring autoactivation. Immunocytochemical analysis identified abundant transgenic protein in mammary tissues in pregnant and lactating mice. (J:18003)
Basic Information
Allele
Strain of Origin
Allele Type
Mutation
Inheritance
Gene Expression
Related Disease
Reference
Phenotypes
Legend：
hm: homozygous
ht: heterozygous
cn: conditional genotype
cx: complex: > 1 genome feature
tg: involves transgenes
ot: other: hemizygous, indeterminate,...
(F): Female
(M): Male
phenotype observed
N: normal phenotype
(#): related diseases count
Phenotypes：
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| Phenotypes |
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References Literature
Title
PMID
Journal
Year
IF
