The transgenic construct contained full length murine Tert cDNA adjoined to the bovine KRT5 regulatory region, active in basal keratinocytes. Upregulation of telomerase activity was observed in stratified epithelia of uterus, trachea, and skin tissue obtained from transgenic mice. (J:69757)
Legend:
cx: complex: > 1 genome feature ot: other: hemizygous, indeterminate,... (F): Female
(M): Male
N: normal phenotype
(#): related diseases count