Human HOX11 cDNA was placed under the control of the murine Igh-V region promoter fused to the IgH enhancer. Expression of HOX11 was detected in the kidney via Northern blot analysis and in bone marrow and speen tissue via RNAse protection. Founder mice carried between 2 and 4 copies of the transgenic construct. (J:52782)
Legend:
cx: complex: > 1 genome feature ot: other: hemizygous, indeterminate,... (F): Female
(M): Male
N: normal phenotype
(#): related diseases count