A sequence fragment from the murine Hsp70-1 locus encompassing 655 bp of the 5' flanking and noncoding sequence was adjoined to sequence encoding cre recombinase. Two tandem integrations of the transgenic construct were identified in the founder line. Transgene expression occurred early in embryogenesis, resulting in the production of progeny exhibiting complete recombination of reporter constructs. (J:60711)

Basic Information

Allele
Strain of Origin
Allele Type
Mutation
Inheritance
Gene Expression
Related Disease
Reference
C57BL/6J x CBA
--
Insertion
--
--
--
13

Phenotypes

Legend:
hm: homozygous
ht: heterozygous
cn: conditional genotype
cx: complex: > 1 genome feature
tg: involves transgenes
ot: other: hemizygous, indeterminate,...
(F): Female
(M): Male
phenotype observed
N: normal phenotype
(#): related diseases count
Phenotypes:
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Phenotypes

References Literature

Title
PMID
Journal
Year
IF
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